Nested Russian Doll - like Genetic Mobility Drives Rapid Dissemination of the 1 Carbapenem Resistance Gene bla KPC
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244 words 26 Main text: 4376 words 27 . CC-BY 4.0 International license peer-reviewed) is the author/funder. It is made available under a The copyright holder for this preprint (which was not . http://dx.doi.org/10.1101/033522 doi: bioRxiv preprint first posted online Dec. 2, 2015;
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Nested Russian Doll - like Genetic Mobility Drives Rapid Dissemination of the 1 Carbapenem Resistance Gene bla
244 words 26 Main text: 4376 words 27 . CC-BY 4.0 International license peer-reviewed) is the author/funder. It is made available under a The copyright holder for this preprint (which was not . http://dx.doi.org/10.1101/033522 doi: bioRxiv preprint first posted online Dec. 2, 2015;
متن کاملNested Russian Doll-Like Genetic Mobility Drives Rapid Dissemination of the Carbapenem Resistance Gene blaKPC
The recent widespread emergence of carbapenem resistance in Enterobacteriaceae is a major public health concern, as carbapenems are a therapy of last resort against this family of common bacterial pathogens. Resistance genes can mobilize via various mechanisms, including conjugation and transposition; however, the importance of this mobility in short-term evolution, such as within nosocomial ou...
متن کاملNested Russian Doll - like Genetic Mobility Drives Rapid Dissemination
244 words 26 Main text: 4376 words 27 . CC-BY 4.0 International license peer-reviewed) is the author/funder. It is made available under a The copyright holder for this preprint (which was not . http://dx.doi.org/10.1101/033522 doi: bioRxiv preprint first posted online Dec. 2, 2015;
متن کاملEmergence of KPC-2 and KPC-3 in carbapenem-resistant Klebsiella pneumoniae strains in an Israeli hospital.
Carbapenem resistance due to KPC has rarely been observed outside the United States. We noticed a sharp increase in carbapenem-resistant Klebsiella pneumoniae strains possessing KPC in Tel Aviv Medical Center from 2004 to 2006. Sixty percent of the isolates belonged to a single clone susceptible only to gentamicin and colistin and carried the bla(KPC-3) gene, while almost all other clones carri...
متن کاملNational Surveillance Study on Carbapenem Non-Susceptible Klebsiella pneumoniae in Taiwan: The Emergence and Rapid Dissemination of KPC-2 Carbapenemase
OBJECTIVES The global spread and increasing incidence of carbapenem non-susceptible Klebsiella pneumoniae (CnSKP) has made its treatment difficult, increasing the mortality. To establish nationwide data on CnSKP spread and carbapenem-resistance mechanisms, we conducted a national surveillance study in Taiwanese hospitals. METHODS We collected 100 and 247 CnSKP isolates in 2010 and 2012, respe...
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